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Semaglutide vs Ozempic vs Wegovy vs Mounjaro

Semaglutide vs Ozempic vs Wegovy vs Mounjaro: What’s the Difference?

Semaglutide, Mounjaro, Wegovy, and Ozempic can help patients lose a considerable amount of weight. In fact, the quantity of weight loss achievable with these medications is similar to that of surgical interventions. Visit the Wellness Center of Greater Cleveland to learn more. For more information, contact us or book an appointment online. We are conveniently located at 25111 Country Club Blvd Suite 235, North Olmsted, OH 44070.

Semaglutide vs Ozempic vs Wegovy vs Mounjaro in Cleveland, OH
Semaglutide vs Ozempic vs Wegovy vs Mounjaro in Cleveland, OH

Table of Contents:

What is the difference between Semaglutide, Ozempic, Wegovy and Mounjaro?
What are Semaglutide, Mounjaro, Wegovy and Ozempic approved for?
Which one do we choose?
Does Semaglutide, Mounjaro, Wegovy and Ozempic help keep weight off long term?

What is the difference between Semaglutide, Ozempic, Wegovy, and Mounjaro?


Both Ozempic and Wegovy utilize the active ingredient Semaglutide, classified under the glucagon-like peptide-1 (GLP-1) receptor agonists. They serve distinct purposes, with Ozempic designed for treating type 2 diabetes and Wegovy specifically indicated for obesity. Despite its original intention for diabetes management, Ozempic is also prescribed for weight loss in obese patients. Both medications share that they are Semaglutide-based and operate in a similar fashion, although Wegovy boasts a higher maximum dose.

By regulating blood sugar levels, extending the sensation of fullness between meals, and reducing cravings, both Wegovy and Ozempic contribute to weight loss. The prolonged presence of food in the stomach enhances the feeling of fullness. 

Mounjaro is employed in the management of type 2 diabetes in conjunction with diet and exercise. Although it shares a similar purpose with other medications, it differs slightly from Ozempic and Wegovy. Mounjaro focuses on GLP-1 and glucose-dependent insulinotropic polypeptide (GIP), which play crucial roles in regulating blood sugar levels and aiding in weight loss for patients.

Mounjaro slows the digestive system while decreasing the appetite to cause patients to lose weight as well. By targeting two hormones with such crucial metabolic roles, patients can experience considerable weight loss.

What are Semaglutide, Mounjaro, Wegovy, and Ozempic approved for?


While both Mounjaro (Tirzepatide) and Ozempic and Wegovy (Semaglutide) have the potential to induce weight loss, only Wegovy is officially approved by the FDA for this purpose. However, Mounjaro and Ozempic are often prescribed off-label to treat weight loss due to their tremendous efficacy in doing so.

People can lose weight on all three of these medications even though Mounjaro and Ozempic both only have FDA approval for diabetes and blood sugar management. Despite lacking FDA approval, all of these medications have been studied to be safe and their capacity to suppress appetite and help individuals feel fuller can lead to weight loss. Metabolism and blood sugar are also helpful as the medications help your body to secrete insulin.

Which one do we choose?


When it comes to which medication to choose there is no wrong answer. However, each patient’s unique needs will be considered ahead of prescription. In consultation with the specialists at the Wellness Center of Greater Cleveland, a custom medical weight loss management treatment plan will be devised with patient input.

Mounjaro, Wegovy, and Ozempic are administered on a weekly basis through subcutaneous injections in the abdomen, thigh, or upper arm. These medications are complemented by a reduced-calorie diet and exercise regimen.

All of the medications are associated with minimal side effects that mostly wear off after the initial injection period. These side effects are easy to handle such as temporary nausea. Afterwards, by adhering to their dosing schedule and making the appropriate lifestyle changes patients can experience tremendous weight loss benefits from any of these medications.

Does Semaglutide, Mounjaro, Wegovy, and Ozempic help keep weight off long term?


Semaglutide, Mounjaro, Wegovy, and Ozempic can help patients lose a considerable amount of weight. In fact, the quantity of weight loss achievable with these medications is similar to that of surgical interventions.

However, when it comes to keeping off the weight long term, lifestyle interventions such as diet and exercise will be necessary. Similar to other prescription medications, their impact diminishes once you discontinue usage.

While these medications can prompt considerable and quick weight loss, it’s important to note that their effects are temporary. However, with appropriate lifestyle interventions and a comprehensive medical weight loss management plan you can discuss with the specialists at Wellness Center of Greater Cleveland, there is no reason patients cannot enjoy these effects over the long term.

Semaglutide, Mounjaro, Wegovy, and Ozempic are available at the Wellness Center of Greater Cleveland. We serve clients from Cleveland OH, North Olmsted OH, Olmsted Falls OH, North Ridgeville OH, Bay Village OH, Lakewood OH, Berea OH, Brooklyn OH, and BEYOND.